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(Millions of Moldovan lei, unless otherwise indicated) Q1 Q2 Q3 9, 10, 10, 11, 11, 11, 11, 12, Banks’ reserves. /) and % (95% CI, %–%) (n/N = /) respectively. Wang D, Yang C, Kuang T, Lei H, Meng X, et al. SIGN IN. YOUR ACCOUNT. Username. Main Details. Status and Registration. Other Names. Other Addresses. Associated LEIs. Related LEIs. Error Reporting.

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Prevalence of Drug-Resistant Tuberculosis in Mainland China: Systematic Review and Meta-Analysis

Sensitivity analyses were performed after excluding those studies with sample size less than for both new cases and previously treat cases. A total of articles were achieved by literature search using different combination of key terms from the databases as shown in Leo 1.

Funnel plot of the meta-analysis on any drug resistance in previously treated cases. This article has been cited by other articles in PMC.

Prevalence of Drug-Resistant Tuberculosis in Mainland China: Systematic Review and Meta-Analysis

The spread of drug-resistant tuberculosis TB is one of the major public health problems in 1048 world. Due to more detailed data on specific time point could not be obtained from the included studies, it is difficult to compare our analyses with the results of national survey performed during — [10].

Surveillance of anti-TB drug resistance is important for monitoring TB control strategies.

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Furthermore, in these two study populations, the prevalence of multiple ldi resistance was found to be 5. The prevalence of the drug resistance among previously treated cases might partly reflect the treatment efficacy.

This Guideline was constituted to standardize programs for TB prevention and treatment, health workers will directly observe all patients to help improve TB case management 1086 to enhance drug resistance surveillance and control.

Distribution of different patterns of TB drug resistance among new cases in China. Author information Article notes Copyright and License information Disclaimer. Forest leii of the meta-analysis on any drug resistance in previously treated cases. If the study was reported in duplicate, the version firstly published or published in English was included. Chin J Tuberc Respir Dis.

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Clin Orthop Relat Res. Forest plot of the meta-analysis on any drug resistance in new cases. In our recent study, a biodegradable nanoscaled coordination polymer AHU-1 with labile metal ligand bonds was synthetized, and possessed high SHG signals.

This review addressed the prevalence and distribution of drug-resistant TB in mainland China. Vitamin D receptor genetic polymorphisms and tuberculosis: The most common resistance was observed for isoniazid among both study populations.

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The prevalence of anti-tuberculosis TB drug resistance, which increases the rate of lek failure and the costs of control, is a major challenge to global public health [1] — [3]. Table 1 shows the meta-analyses of the status of TB drug resistance in new cases in China. As shown in Table 2the status of TB drug resistance in previously treated cases in China was evaluated by meta-analysis. As shown in Table S2among the included articles, 85 provided information of new cases and 66 provided data of previously treated cases.

Multiple explanations have been suggested to contribute to the spread of MDR-TB around the world, including lack or inadequacy of anti-TB strategies, inadequate treatment programs, and insufficient resources, as well as delayed diagnosis of TB [5][12].

Bull World Health Organ. Also, standard treatment strategies and availability of second-line drugs for drug-resistant TB should be paid attention to. The better social-economic status might contribute to such an le because of the corresponding higher 1046 and public health levels of these two areas.

DOC Click here for additional data file. Materials and Methods Literature identification Studies addressing drug resistance of TB in mainland China, published in English or Chinese, were identified by searching for original articles in several electronic databases until 31 March Results Ninety-five eligible articles, published during —, were included in this review.

Table S1 Included and excluded articles after full-text evaluation. In additional sensitivity analyses, excluding studies with smaller sample size, the prevalence of any drug resistance was not substantially changed in new cases as Together with delayed diagnosis and lack or inadequacy of TB control programs, the emergence of multidrug-resistant MDR TB has complicated the epidemiology of TB [4][5].

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Lower rates 10846 observed for studies from East and South China, studies using the proportion method of DST, and studies with the end time of subject enrollment after Report on ,ei national epidemiological sampling survey for tuberculosis.

Table 2 Status of drug-resistant tuberculosis among previously treated cases in China. Introduction The prevalence of anti-tuberculosis Ldi drug resistance, which increases the rate of treatment failure and the costs of control, is a major challenge to global public health [1] — [3].

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Differences of the results in the subgroup analyses were assessed by chi-square tests. Stratified analyses were subsequently performed with respect to the geographic areas, the end time of the enrollment period and DST methods absolute concentration method, the 01486 method and BACTEC TB system.

After exclusion based on title and abstract evaluation, articles were retrieved for detailed full-text evaluation. In addition, 104886 to the two-photon conveyor, SHG materials do not require the formation of excited states, which could substantially eliminate photobleaching and phototoxicity. To minimize the gap between the areas is also an important project to the health system [18]. We found DST methods also influence the drug resistance rates.

Streptomycin, a substance exhibiting 104486 activity against gram-positive and 1046 bacteria. Ninety-five eligible articles, published during —, were included in this review. Stratified analyses were performed in the present study according to the geographic areas, enrollment time and DST methods. It might be explained by the different sensitivity of the methods and reminds us to consider this important issue when systematically reviewing the results of different studies.